Subscribe

Receive updates about our latest products in your inbox

Register For Our Next Webinar

Rewiring the Brain for Weight Loss

About Us

For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional

Search the Blog

  • There are no suggestions because the search field is empty.

Melatonin – Not Just for Sleep

Structural_modelWe understand melatonin helps with sleep, but in a recent analysis of eight randomized controlled trials, melatonin supplementation was found to improve blood lipid status. Using a meta-analysis approach, a “significant association between melatonin supplementation and a reduction in triglycerides (WMD: −31.54 mg/dL, 95% CI: −50.71, −12.38, p = 0.001) and total cholesterol levels (WMD: −18.48 mg/dL, 95% CI: −35.33, −1.63, p = 0.032)” was observed. No significant effect on LDL-C (WMD: −2.37 mg/dL, 95% CI: −11.61, −6.86, p = 0.615) and HDL-C (WMD: 1.28 mg/dL, 95% CI: −0.66, 3.23, p = 0.197) was found. A sub-group analysis found “a significant decrease in triglycerides at doses ≥8 mg/d when trials last[ed] ≥8 weeks. 

In addition, “a significant decrease of total cholesterol was [also] found at doses ≥8 mg/d, and when total cholesterol baseline levels were ≥200 mg/dL.”  Overall, the results indicate that melatonin supplementation has notable effects on triglycerides and total cholesterol levels, and is more evident with “higher dose and longer duration, and also [with] a higher concentration of cholesterol levels.”  Further studies are required to determine the benefits of melatonin on lipid profile.

Ref.:  Mohammadi-Sartang M, Ghorbani M, Mazloom Z. Effects of melatonin supplementation on blood lipid concentrations: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr. 2017 Nov 16. pii: S0261-5614(17)31401-2. doi: 10.1016/j.clnu.2017.11.003. [Epub ahead of print]

 

Related Biotics Research Product: PheniTropic Ultra PMMelatonin-B6/MG

Submit your comment

Related Post