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17 May

Magnesium and Vitamin D, Better Together

Oftentimes, we focus on a single nutrient and how it impacts our physiology. However, one study recently highlighted the importance of remembering the synergy between nutrients. Magnesium and vitamin D, for example, are two such nutrients who prove to be better off together than alone. In a...

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10 May

Nutrients Turned to Toxins in Chronic Kidney Disease

Our gut microbiota process food nutrients in such a way that can generate uremic toxins or precursors metabolized to toxins in patients with chronic kidney disease (CKD). Some key uremic toxins include Trimethylamine N-Oxide (TMAO), p-cresyl-sulfate (pCS), indoxyl-sulfate (IS) and indole-3...

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03 May

Diabetes in the Gut

When thinking about diabetes and dysmetabolism, we look at a number of tissues such as adipose, liver, muscle and pancreas, but are we considering enough the role of the gut? Metabolic syndrome is defined as a cluster of physiological abnormalities that increase the risk of developing...

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26 Apr

Vitamin K2 Protects Against Bone Loss in Women

Vitamin K2, a cofactor in the carboxylation of osteocalcin, is recognized as a protector against bone loss and fractures in postmenopausal women. Functionally, the availability of vitamin K regulates the carboxylation of osteocalcin. “Epidemiological studies have found associations between serum...

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19 Apr

Sleep, Detox for the Brain

As if we needed another reason to get enough sleep! A hot-off-the-press study entitled, “β-Amyloid accumulation in the human brain after one night of sleep deprivation,” recently appeared in PNAS (Proceedings of the National Academy of Sciences). Although there have been previous studies...

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12 Apr

Melatonin – Not Just for Sleep

We understand melatonin helps with sleep, but in a recent analysis of eight randomized controlled trials, melatonin supplementation was found to improve blood lipid status. Using a meta-analysis approach, a “significant association between melatonin supplementation and a reduction in...

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05 Apr

Gut Microbiota Influencing Obesity

Polyphenols may generate numerous health benefits by modulating the gut microbiota (GM).  Phytochemicals that can influence GM have recently been studied as adjuvants to support healthy weight and inflammatory response. These phytochemicals include polyphenols and their derivatives, carotenoids,...

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29 Mar

Migraine and Cardiovascular Risk

According to the Headache Classification Committee of the International Headache Society,[1] migraine affects nearly 15% of the population or about one billion people worldwide. In a general population cohort, performed by Adelborg K, et al., various risk factors in patients with migraine...

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22 Mar

Folate Deficiency Associated with Gene Modulation

Folate deficiency has been associated with the onset of varied metabolic abnormalities, “including insulin resistance, by altering epigenetic processes on key regulatory genes,” such as the calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2). CAMKK2 is part of the calcium-triggered...

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15 Mar

Vitamin D and the Flu

Utilizing a randomized, open, controlled clinical trial, a study was performed to “evaluate the clinical efficacy and safety of vitamin D” for the prevention of influenza A in infants. Infants were randomized to low-dose or high-dose vitamin D, for four months, with 200 infants in each group....

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