---
title: How to Diagnose Non-Celiac Gluten Sensitivity:
description: How to Diagnose Non-Celiac Gluten Sensitivity:
---

[Research Forum ](https://info.bioticsresearch.com/researchforum)

# [How to Diagnose Non-Celiac Gluten Sensitivity:](https://info.bioticsresearch.com/researchforum/2017/08/05/how-to-diagnose-non-celiac-gluten-sensitivity-2)

 Written by [admin](https://info.bioticsresearch.com/researchforum/author/admin) | Aug 5, 2017 2:49:21 PM

Non-Celiac Gluten Sensitivity (NCGS) is a syndrome characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease (CD) or wheat allergy (WA). Although NCGS is triggered by gluten-containing cereals, the offending dietary protein has not been identified yet, and could include other components such as amylase-trypsin inhibitors (ATIs). Indirect evidence suggests that NCGS is more common than CD. Using a self-administered evaluation incorporating a modified Gastrointestinal Symptom Rating Scale, the patient identifies 1 to 3 main symptoms that are quantitatively assessed using a Numerical Rating Scale ranging from 1 to 10. The double-blind placebo-controlled gluten challenge (8 g/day) includes a one-week challenge followed by a one-week washout of strict gluten free diet (GFD) and by the crossover to the second one-week challenge. The vehicle should contain cooked, homogeneously distributed gluten. A variation of 30% of 1 to 3 main symptoms between the gluten and the placebo challenge should be detected to discriminate a positive from a negative result. Note that NCGS may be transient, therefor gluten tolerance needs to be re-assessed in patients with NCGS. 

Carlo Catassi, et al. Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria. Nutrients. 2015 June; 7(6): 4966-4977.

 

Share This: 

 

[View full post](https://info.bioticsresearch.com/researchforum/2017/08/05/how-to-diagnose-non-celiac-gluten-sensitivity-2)

```json
{
  "@context" : "http://schema.org",
  "@type" : "BlogPosting",
  "author" : {
    "@type" : "Person",
    "name" : "admin"
  },
  "dateModified" : "2020-09-02T05:51:05.696Z",
  "datePublished" : "2017-08-05T14:49:21Z",
  "headline" : "How to Diagnose Non-Celiac Gluten Sensitivity:",
  "image" : {
    "@type" : "ImageObject",
    "height" : 1272,
    "url" : "https://f.hubspotusercontent10.net/hubfs/4004166/bioticresearch_blog_assets/Gluten-free-food.jpg",
    "width" : 1908
  },
  "mainEntityOfPage" : "https://info.bioticsresearch.com/researchforum/2017/08/05/how-to-diagnose-non-celiac-gluten-sensitivity-2",
  "publisher" : {
    "@type" : "Organization",
    "logo" : {
      "@type" : "ImageObject",
      "height" : 60,
      "url" : "/hs/hsstatic/content_shared_assets/static-1.4092/img/default-amp-logo.png",
      "width" : 60
    },
    "name" : "Research Forum"
  }
}
```