---
title: "B’s and Omega-3’s: Better Together for Brain Health"
description: Too often, we look at the physiological effect of different nutrients in isolation, however, more and more research is uncovering the synergistic benefits of nutrients in combination. Take omega-3s and B vitamins, for example. An unlikely pair, they have been shown to work better together when examining brain health and cognition.
---

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# [B’s and Omega-3’s: Better Together for Brain Health](https://info.bioticsresearch.com/researchforum/bs-and-omega-3s-better-together-for-brain-health)

 Written by [The Biotics Research Team](https://info.bioticsresearch.com/researchforum/author/the-biotics-research-team) | Aug 16, 2018 2:06:34 PM

Too often, we look at the physiological effect of different nutrients in isolation, however, more and more research is uncovering the [synergistic benefits](https://blog.bioticsresearch.com/the-fat-soluble-philharmonic) of nutrients in combination. Take omega-3s and B vitamins, for example. An unlikely pair, they have been shown to work better together when examining brain health and cognition.

Research has already determined that B vitamin supplements may support memory and learning in elderly patients, and, also, omega-3s are strongly associated with neuroprotective benefits, but newer research suggests these benefits magnify when the two are combined. 

One [Oxford University study](https://www.researchgate.net/publication/319123963_Two_nutrients_are_better_than_one_B-vitamins_and_omega-3_fatty_acids_in_the_prevention_of_dementia) looked at whether or not lowering homocysteine levels by supplementing with high-dose-B-vitamins (folate, B6 and B12) would influence people with mild cognitive impairment (MCI). They also tested baseline plasma omega-3 fatty acid levels to further investigate its role. Because MCI, defined as a subtle decline in cognitive function, may be a [prodrome of clinical dementia and Alzheimer’s Disease](https://www.ncbi.nlm.nih.gov/pubmed/16631882), any information that may help in maintaining healthy cognition is important. 

In those with increased homocysteine levels, supplementing with B-vitamins over a two-year period did, in fact, slow the rate of brain atrophy, particularly in those regions susceptible to Alzheimer’s Disease. Those subjects also clearly demonstrated a slowing down of cognitive decline. What they found, however, was that these effects were greatly enhanced in those people with high baseline levels of omega-3 fatty acids versus those with lower levels, suggesting that yes, B-vitamins are effective, but the cognitive benefits may be enhanced with a higher levels of omega-3 fatty acids in the body.

The takeaway? Take your Bs with omega-3s for better brain health!

 

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