---
title: Melatonin supports Lung Health in New Study
description: Melatonin, a well-known antioxidant molecule that supports healthy inflammation, may protect lung health threatened by viral and other pathogens.
---

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# [Melatonin supports Lung Health in New Study](https://info.bioticsresearch.com/researchforum/melatonin-protects-lung-health-in-new-study)

 Written by [The Biotics Research Team](https://info.bioticsresearch.com/researchforum/author/the-biotics-research-team) | Apr 6, 2020 8:19:25 PM

Melatonin, a well-known antioxidant molecule that supports healthy inflammation, may protect lung health threatened by viral and other pathogens. A [recent study](https://www.sciencedirect.com/science/article/pii/S0024320520303313) produced data showing that melatonin may act to protect lung health, and could benefit COVID-19 patients.

The study authors suggest that excessive inflammation, oxidation, and an exaggerated immune response very likely contribute to COVID-19 pathology, leading to a cytokine storm and subsequent progression to further health complications. Their article summarizes the likely benefits that melatonin may offer.

Melatonin is not directly antagonistic to pathogens, but it has [indirect](http://www.melatonin-research.net/index.php/MR/article/view/71) antagonistic actions due to its pro-healthy inflammation, anti-oxidation and immune enhancing features. Melatonin has been linked to protecting the lung when otherwise vulnerable to oxidative injury, pro-inflammatory cytokine release and inflammatory cell recruitment.

Melatonin is known to support healthy inflammation effects through various pathways, as well as showing anti-oxidative actions that up-regulate anti-oxidative enzymes, down-regulate pro-oxidative enzymes, and possibly exert a direct action of scavenging free radicals.

Previous studies have also demonstrated an [immunomodulating](https://onlinelibrary.wiley.com/doi/full/10.1111/j.0959-9673.2006.00474.x) effect of melatonin, improving proliferation and maturation of natural killer cells, T and B lymphocytes, granulocytes and monocytes. Researchers have also noted that melatonin showed promising results regarding the attenuation of circulating [cytokines](https://insights.ovid.com/crossref?an=00005792-201807270-00012).

Considering the role of melatonin in these various physiological processes, a patient’s melatonin levels could possibly be linked to a higher vulnerability to health complications due to viruses, as seen in the elderly population with lower melatonin levels due to [aging](https://www.ncbi.nlm.nih.gov/pubmed/15582288).

The primary study authors suggest that, although the direct evidence of melatonin application in COVID-19 is unclear, both its use in experimental animal models and in studies on humans has documented its efficacy and safety and that its use by COVID-19 patients may be beneficial.

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