This study is consistent with the association observed in adults. Ninety-four studies were included in a meta-analysis which found an increase in MS prevalence at higher latitudes, and a systematic review of 10 studies and nearly 152,000 participants with MS found not only was latitude a risk factor, but the month of birth was also a significant risk factor. For example, individuals born in May had an 11% greater risk for a diagnosis of MS, while those born in November had a 12% lower risk. These results strongly suggest that maternal sun exposure is an important factor for subsequent risk. While a causal link has not been established, it is widely suspected that vitamin D availability drives the association. In a recent systematic review and meta-analysis, higher gestational vitamin D levels were associated with a 37% risk reduction for a diagnosis of MS later in life.