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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
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Easy direct-to-patient ordering & fulfilment for Lifelong Wellness, eStoreRx™ is offered as part of the WholePractice membership or as a stand-alone program.
November 14 2024
Exciting research is being done in the burgeoning field called Metabolic Psychiatry, which is dedicated to addressing the bioenergetic underpinnings o...
An interesting study found the effectiveness of deer antler to help with fatigue in mice may be caused by alterations in the expression of genes related to skeletal muscle strength.
Deer antler is well-known in traditional Chinese medicine for its use in combating fatigue and supporting physical strength as well as overall health. Yet most deer antler studies have focused on the sike deer antler. Just a few have investigated sambar deer antler activities.
Researchers have shown that the protein extract from sika deer antler base might increase mice swimming time. It is thought that the mechanism behind this benefit might be the activation of lactate dehydrogenase activities, which reduce blood lactic acid levels and serum urea nitrogen. However, the anti-fatigue pathways of deer antler remain unclear.
This featured study, however, examined the anti-fatigue effects of Formosan sambar deer tip antler extract (FSDTAE) during a forced-swimming test and evaluated the mechanisms by microarray.
The results showed that mice administered FSDTAE for 28 days had longer exhaustion times. However, the indicators of fatigue - a reduction in glucose levels and an increase in blood urea nitrogen and lactic acid levels - were not significantly inhibited by FSDTAE. A further microarray analysis showed that the genes in 9 different signaling pathways were affected, with the most enriched category being the muscular system. The most upregulated genes were responsible for the development and contraction of muscle.
The researchers concluded that the mechanism behind the anti-fatigue and muscle strength enhancement effects in mice could be the upregulation of the genes responsible for muscle contraction.
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A recent study found that deer antler’s potential use in helping with fatigue in mice may be caused by alterations in th...
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