Multiple studies published recently have added to the body of evidence demonstrating harm from the consumption of ultra-processed food. Published in the American Journal of Medicine, a random sample of nearly 5,000 adult participants in the most recent NHANES study (2021-2023) was used to estimate the effect of ultra-processed food on cardiovascular disease, specifically, heart attack and stroke risk. In this sample of middle-aged adults (mean age 55), the average intake of ultra-processed food accounted for 26.1% of total energy intake. The risk of cardiovascular disease was 47% higher in the highest quartile compared with the lowest quartile. For comparison, the large prospective UK Biobank cohort found a 45% greater risk for heart failure and 62% higher risk for cardiovascular mortality when comparing the highest quartile of sedentary behavior to a lower quartile. In another large study of older U.S. adults, ultra-processed foods accounted for 42% of total calories, and higher intakes were associated with impaired executive functioning. JAMA Network Open also recently published evidence linking ultra-processed food to harm among children. In a cohort of over 2000 Canadian children assessed using a food frequency questionnaire at age 3, ultra-processed food accounted for 45.5% of total caloric intake. By age 5, behavior was assessed with the Child Behavior Checklist (CBCL), a validated tool used by caregivers to describe a range of behavioral and emotional symptoms, with a higher score indicating more caregiver-reported problems. Each 10% increase in calories derived from ultra-processed food was associated with higher total CBCL scores, as well as internalizing (inward-focused, such as anxiety and depression) and externalizing (outward-directed, e.g., aggression, hyperactivity) scores.