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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
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November 21 2024
The protective association between dietary flavonoid intake and the risk of dementia has been the focus of yet another study; this one being published...
In a study performed by Ghana B., et al. the value of vitamin D supplementation was assessed in patients with chronic low back pain (CLBP). A high prevalence of hypovitaminosis D (50-90%) was observed in the study group, attributed to low dietary intake, skin color, and “changing lifestyle”, despite ample sunlight. The patients (18-75 year olds) had CLBP for <-3 months, and were not responding to medical or physical therapies. Their pain score was >- 50 on a 0 – 100 visual analog scale, and the mean baseline of vitamin D was 12.8 ng/mL.
This study involved two phases; an induction phase and a maintenance phase. In the induction patients received a dose of 60,000 IU of vitamin D3 orally each week for 8 weeks. In those patients with vitamin D levels <5mg/mL, 60,000IU/day of vitamin D3 was administered once daily for the initial 5 days, then they received supplementation as noted above for eight weeks. After the initial 8-week induction phase, if the vitamin D remained below 29 ng/mL, the regimen was repeated. In the maintenance phase patients were given 60,000IU/month for six months. Following six months of therapy two-thirds of the group achieved normalization of vitamin D. A significant reduction in pain scores were also observed, as well as improved disability, which increased over the six months. Serum vitamin D levels increased significantly, to 36.07 post supplementation (p<0.01). Of the group 45 (66%) attained normal vitamin D levels (>29ng/mL), while 18 (27%) remained insufficient and 5 (7%) remained deficient.
Although a single-arm, open-label study, without concomitant assessment of medication use, this study demonstrated an improvement in pain and disability with vitamin D supplementation in patients with CLBP.
Ghai B, Bansal D, Kanukula R, Gudala K, Sachdeva N, Dhatt SS, Kumar V. Vitamin D Supplementation in Patients with Chronic Low Back Pain: An Open Label, Single Arm Clinical Trial. Pain Physician. 2017; 20:E99-E105 • ISSN 2150-1149
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