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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
November 21 2024
The protective association between dietary flavonoid intake and the risk of dementia has been the focus of yet another study; this one being published...
Results of a large population-based observational cohort study examining the association between weight loss and diabetes remission were recently published in PLOS Medicine. This Hong Kong-based study included more than 37,000 people recently diagnosed with type 2 diabetes who were followed for a median of 8 years, with a focus on their 1-year weight change after diagnosis and their long-term remission rates.
The authors found that only 6% of people achieved remission (defined as 2 consecutive HbA1c <6.5% and no glucose-lowering medications), but the likelihood of remission was greater with a higher degree of weight loss. For example, there was a more than 3-fold (328%) greater chance of remission with ≥10% weight loss (compared to weight gain), versus only a 34% change when losing between 0-5%. Additionally, approximately 2/3 of people that achieved remission eventually returned to hyperglycemia, again, strongly associated with the degree of weight loss. Remission in this study was associated with a 31% lower all-cause mortality rate.
The authors suggest this large population-based cohort provides important insights, as the controlled conditions in clinical trials may not always accurately reflect real-world dynamics. For example, in a randomized trial, a total diet replacement (as part of an aggressive weight loss strategy) was shown to induce remission in nearly ½ of the participants recently diagnosed with diabetes, compared to only 4% in the control group (an odds ratio of 19.7). Furthermore, in this randomized trial, only 7% of those losing 0-5 kg achieved remission, compared to 86% of those who lost 15kg or more (and none of those who gained weight). These studies both strongly suggest weight loss should be heavily emphasized following a diabetes diagnosis, and that perhaps real-world efforts are not nearly aggressive enough.
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