Shop
eStoreRx™
Online Supplement Dispensary
Easy direct-to-patient ordering & fulfilment for Lifelong Wellness, eStoreRx™ is offered as part of the WholePractice membership or as a stand-alone program.
For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
This inclusive membership contains all of the the tools you need to grow your business, including WholeLifeRx™, Nimativ®, WholeLifeQ™, eStoreRx™ and Practice Success Programs.
Easy direct-to-patient ordering & fulfilment for Lifelong Wellness, eStoreRx™ is offered as part of the WholePractice membership or as a stand-alone program.
April 29 2024
A new study published in the Journal of the American College of Cardiology provides some mechanistic insight into the benefits of physical activity fo...
A recent study published in Clinical Nutrition adds additional evidence to what we covered in a past blog article: ketogenic diets may be beneficial for people living with McArdle disease (glycogen storage disease type V).
The primary defect in McArdle disease is absence or deficiency of the enzyme myophosphorylase, responsible for muscle glycogen breakdown. This deficit results in intolerance to physical activity, and activity-induced muscle pain and muscle damage (typically indicated by dramatically elevated creatine kinase). Being that individuals with this condition can’t rely on glucose to fuel skeletal muscle, it stands to reason that shifting the muscles to run primarily on fatty acids – as occurs on ketogenic diets – may reduce symptoms and improve physical endurance and quality of life.
The study randomized subjects to follow either a modified ketogenic diet (75-80% fat, 15% protein, 5-10% carbohydrates) or an isocaloric placebo diet (45-50% fat, 15% protein, 35-40% carb) for a period of 3 weeks and then switch to the other diet, separated by a washout period of a minimum of 13 days. If you’re wondering how a “placebo” was created for a ketogenic diet (after all, you know for certain whether you’re following a keto diet or not), the diets are described as follows:
“Participants were instructed to follow a meal plan that was identical for the two diets and included 3 meals and 1-2 snack(s). Each meal consisted of 1 protein, 2-4 carbohydrate, and 2-3 fat choices chosen from an ingredient list. At every meal and snack, the participants had to consume a carefully measured amount of a blinded liquid-supplement, which accounted for approximately 67% of the daily caloric intake.”
Diet compliance was assessed via a food journal. Despite efforts at blinding, ten out of fifteen subjects who completed both diets could tell which diet they were on during the given period.
Compared to the higher-carb diet, subjects experienced significant increases in fat oxidation and plasma β-hydroxybutyrate, and an approximately 20% increase in maximal exercise capacity, along with significant improvements in patient-reported outcomes (fatigue severity and physical functioning). It will be interesting to see what happens in longer-term studies, but this small trial is a start to generate clinical evidence for what many McArdle patients have already discovered for themselves: keto diets improve numerous parameters of overall functioning and wellbeing.
Submit this form and you'll receive our latest news and updates.
A study published recently in Cell Reports Medicine showed that a ketogenic diet is safe, feasible, and may be a benefic...
Learn moreA paper published recently in Current Obesity Reports presents evidence for the efficacy of ketogenic diets for lipedema...
Learn more“Summarizing the extensive scientific evidence, the ketogenic diet is a promising nutritional model in the context of ca...
Learn more
*These statements have not been evaluated by the Food and Drug Administration. This product has not intended to diagnose, treat, cure, or prevent any disease.
© 2023 Biotics Research Corporation - All Rights Reserved
Submit your comment