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Multivitamins: One Size Does Not Fit All

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Pets & Food Allergies

iStock-1165318880Some good news has come out for pet lovers (as if we need more reasons to love our pets!). Recently published in PLoS One, results of the largest to-date birth cohort study in Japan suggest that some pets, especially dogs and cats, are associated with a lower risk for food allergy development in children.

This study utilized data from an ongoing prospective birth cohort study (the Japan Environment and Children’s Study) which collected data on nearly 100,000 mothers and their children (over 60,000 children were followed up to age 3). Questionnaires were used to collect a wide range of data regarding pet exposure and food allergies, as well as many other factors that may contribute to allergy incidence, ranging from the maternal history of allergic diseases, annual household income, use of antibiotics, frequency of vacuuming, breastfeeding practices, and much more. The study had several limitations, such as its observational nature (no causality can be established), and all data were self-reported, including parents’ reports of a physician’s diagnosis.  

The main observations were generally favorable to having pets, as dogs (especially kept indoors) were linked to a lower incidence of egg, milk, and nut allergies, while cats were associated with a lower risk of egg, wheat, and soybean allergies, with the adjusted risk reduction as high as 57%. Only hamsters were linked to a greater allergy risk to any foods, nearly doubling the risk for nut allergy. Timing of exposure also appeared to make a difference – exposure prenatally did not seem to have any effect by itself, but exposure prenatally AND during infancy was required for some effects. Multiple mechanisms were reviewed which may explain these results, including changes to gut microbiota, exposure to endotoxin, and mediated via a skin-barrier mechanism. 

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