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eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
November 14 2024
Exciting research is being done in the burgeoning field called Metabolic Psychiatry, which is dedicated to addressing the bioenergetic underpinnings o...
A systematic review and meta-analysis recently published in the Journal of the Academy of Nutrition and Dietetics examined the effects of vitamin D supplementation in post-menopausal women on both blood pressure and C-reactive protein, a marker of systemic inflammation and cardiovascular disease risk. This analysis included 7 randomized and controlled trials, directly comparing the effects of vitamin D against controls, with 6 arms each for systolic blood pressure, diastolic blood pressure, and C-reactive protein (CRP).
Although no effect on blood pressure was shown in these trials, a significant reduction in CRP (mean difference (MD) of -0.65 mg/L) was observed with vitamin D supplementation, including an MD of -0.91 mg/L in studies with a duration of 3 months or more, and an MD of -2.10 mg/L with doses of 1000 IU per day or less. This significant reduction in CRP is notable, in part because it is an apparent benefit of supplementation; potentially a more clinically relevant finding than the association between lower serum levels of CRP and a higher serum 25-OH vitamin D previously observed in several studies.
This is in line with many previous observational studies, such as a cross-sectional study that found that low 25-OH levels were associated with a nearly 3-fold increase in risk for cardiovascular events, magnified to nearly 5-fold when found in combination with elevated CRP levels. It is also consistent with several previously published meta-analyses of vitamin D supplementation, including a meta-analysis of 8 randomized trials that found vitamin D supplementation reduced CRP and improved glycemic control among participants with cardiovascular disease, and a meta-analysis of 33 trials that found vitamin D supplementation reduced CRP and malondialdehyde, and also improved multiple markers of antioxidant status (e.g., glutathione) among patients with diabetes.
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