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eStoreRx™
Online Supplement Dispensary
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
December 11 2025
An abstract presented at the American Heart Association’s 2025 Scientific Sessions suggests that personalized supplementation with vitamin D cuts the ...
An abstract presented at the American Heart Association’s 2025 Scientific Sessions suggests that personalized supplementation with vitamin D cuts the risk of a heart attack in half among adults with heart disease. While these abstracts present preliminary findings that have not yet been published or peer-reviewed, if validated, this research would be of significant clinical importance.
The study, known as the TARGET-D trial, included 630 adults (with an average age of 63) who were treated for acute coronary syndrome at Intermountain Medical Center in Utah and were randomized to either a vitamin D group or a standard of care group. Rather than a fixed dose of vitamin D, a personalized dose was administered to achieve serum 25-OH vitamin D levels of at least 40 ng/mL (but not exceeding 80 ng/mL), necessitating monitoring every 3 months with dosage adjustments. Notably, 85% of study participants had blood levels below this threshold at baseline, and roughly 52% required doses of more than 5,000 IU to achieve the desired blood levels. Blood calcium levels were also monitored, and once 40 ng/mL was achieved, blood levels were only checked annually.
With an average follow-up of 4.2 years, participants assigned to the vitamin D group had a 52% lower risk of heart attack than those receiving standard of care. Although not yet peer-reviewed and with several limitations, including a small sample size and a lack of diversity among participants, the magnitude of the reduction is substantial. For context, a 2022 meta-analysis published in JAMA Internal Medicine indicates statins reduce the relative risk for myocardial infarction by 29%. Key to the TARGET-D trial appears to be the personalized dosing of vitamin D, necessitating large doses in most participants.
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