Subscribe

Receive updates about our latest products in your inbox

Register For Our Next Webinar

Beyond the Buzzword: Practical Detoxification Strategies for Clinicians

About Us

For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional

Search the Blog

  • There are no suggestions because the search field is empty.

Anabolic Steroid Use and Structural Decline of the Brain

VaccineProlonged anabolic-androgenic steroid (AAS) use has been associated with psychiatric symptoms and cognitive deficits. Researchers investigated the association between long-term AAS exposure and brain morphometry, including subcortical neuroanatomical volumes and regional cortical thickness. Using high-resolution magnetic resonance imaging, they compared 82 weightlifters who had used AASs for longer than one year with 68 weightlifters who had never used AASs or other doping substances. Researchers discovered negative correlations between AAS use and brain volume and cortical thickness, raising concerns about the use of AASs on brain structure. Commenting on the study, Dr. Dubovsky with NEJM Journal Watch Psychiatry commented that steroids readily enter the brain and bind to androgen receptors. The possible mechanisms of steroid-induced neurotoxicity include formation of β-amyloid, oxidative stress, and cardiovascular effects on brain circulation. Consequences include accelerated brain aging, cognitive decline, and dementia, as well as decreased resilience associated with psychiatric syndromes. 

Bjørnebekk A, et al. Structural Brain Imaging of Long Term Anabolic-Androgenic Steroid Users and Non-using Weightlifters. Biol Psychiatry 2016 June 30; doi.org/10.1016/biopsych.2016.06.017

Share This: 
 

Submit your comment

Related Post