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Potassium for Reduced Risk of Stroke

PotassiumResearchers from Italy, Sweden and the USA reviewed the observational cohort studies addressing the relation between potassium intake and the incidence or mortality of total stoke or stroke subtypes published through August 6, 2016.Researchers carried out a meta-analysis of 16 cohort studies based on the relative risk (RR) of stroke, comparing the highest versus lowest intake categories. They also plotted for blood pressure. Relative to the lowest category of potassium intake, the highest category of potassium intake was associated with a 13% reduced risk of stroke in the blood pressure-adjusted analysis. Summary RRs tended to decrease when original estimates were unadjusted for blood pressure. Analysis for stroke subtypes yielded comparable results. Researchers concluded that their meta-analysis shows an inverse associating between potassium intake and risk of total, hemorrhagic, and ischemic stroke, with the lowest risk occurring at a potassium intake of around 90 mmol (≈3,500 mg) per day. They also suggest that the mechanisms by which potassium intake may affect stroke risk can only partially be explained by an effect on blood pressure, particularly for ischemic stroke and in females. Interestingly, the new Recommended Daily Intake (RDI) for potassium has been increased to 4,700 mg!

Vinceti M, et al. Meta-Analysis of Potassium Intake and the Risk of Stroke. J of the Am Heart Assoc. 2016;5:e004210 doi:10.1161/JAHA.116.004210

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