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eStoreRx™
Online Supplement Dispensary
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
December 18 2025
Low-carbohydrate diets are perhaps most popular for weight loss, but the strictest form of carbohydrate restriction – a ketogenic diet – has been show...
Vitamin D has proven to be a champion of cognitive health in a recent study assessing healthy adults who possessed a baseline vitamin D of ≤ 100nmol/L, and located in British Columbia, Canada (54˚ North Latitude).
82 adults were randomized and blinded to receive either high dose vitamin D3 (4000 IU/day) or low dose vitamin D3 (400 IU/day) for 18 weeks. The serum levels of 25(OH)D were observed to increase significantly in the high dose vitamin D group, from 67.2 ± 20 to 130.6 ± 26, compared to the low dose group, which increased from 60.5 ± 22 to 85.9 ± 16 nmol/L (p=0.0001). The high dose group also experienced performance improvement on nonverbal (visual) memory, assessed by the Pattern Recognition Memory task (PRM), (84.1 ± 14.9 to 88.3 ± 13.2) (d = 0.3), as well as the Paired Associates Learning Task, (PAL) number of stages completed, from 4.86 ± 0.35 to 4.95 ± 0.22 (p=0.044) (d=0.5). These improvements were not exhibited in the low dose group. It was also noted that the “degree of improvement was comparatively greater in the high dose group for these tasks.” For those possessing insufficient 25(OH)D at baseline (<75nmol/L), a significant improvement (p=0.005, d=0.7) was demonstrated in the high dose group (n=23) (p=0.005, d=0.7).
“Nonverbal (visual) memory seems to benefit from higher doses of vitamin D supplementation, particularly among those who are insufficient at baseline (<75nmol/L).” Thus, they suggested that “higher 25(OH)D is particularly important for higher level cognitive functioning, specifically nonverbal (visual) memory.”
Ref: Petterson JA. Does high dose Vitamin d supplementation enhance coginition? A randomized trial in healthy adults. Exp. Gerontol. 2017 Apr; 90:90-97. Doi: 10.1016/j.exger.2017.01.019. Epub 2017 Feb 4.
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