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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
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November 26 2024
Results of a study recently published in the European Journal of Nutrition suggest that low levels of magnesium may increase the susceptibility of DNA...
Results of a prospective and longitudinal study conducted among schoolchildren were recently published in Allergology International, describing the association between the gut microbiome and the effectiveness of oral immunotherapy (OIT) for dairy cow’s milk allergy (CMA). Thirty-two children with IgE-mediated CMA received OIT for a period of 13 months, followed by a 2-week period of complete dairy avoidance. The primary outcome being measured was sustained unresponsiveness (SU), i.e., the ability to tolerate without any symptoms a cumulative total dose of cow’s milk of ≥44.4 ml administered by a double-blind placebo-controlled food challenge (DBPCFC), after 2 weeks of complete milk avoidance. Unfortunately, the rate of successful SU following OIT for food allergies is low once OIT is stopped, which is why this study attempted to examine multiple factors, such as changes to the microbiome, which may have influenced the treatment’s effectiveness.
Only 7 (22%) of the children achieved SU after the 2-week avoidance period. Children were less likely to have treatment success if they had higher levels of milk- and casein-specific IgE antibodies initially, and if they were undergoing concurrent treatment of atopic dermatitis or asthma (children with uncontrolled asthma/dermatitis were excluded from the study). For example, the likelihood of achieving SU was 91% and 84% lower with a current diagnosis of dermatitis or asthma, respectively. Microbiome testing revealed that a greater abundance (and increase) of Bifidobacterium was associated with a higher likelihood of SU, as were higher fecal levels of specific monosaccharides associated with mucins, a bacterial energy source. Previous research has found a reduced abundance of Bifidobacterium among children with CMA, warranting controlled studies using probiotics (Bifidobacterium) as a potential means of amplifying OIT treatment success.
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BMC Microbiology recently published a meta-analysis of metagenomic sequencing data from obese and non-obese participants...
Learn moreResults of a small human clinical trial recently published in NPJ Biofilms and Microbiomes indicate that short-term use ...
Learn moreResults of a small pilot study published in May 2023 in Neuroscience explored connections between the gut microbiome and...
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