Shop
eStoreRx™
Online Supplement Dispensary
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
December 20 2024
The British Journal of Sports Medicine recently published a systematic review that analyzed the effects of postpartum exercise on maternal postpartum ...
A recent study on both mice and human subjects has revealed the biological mechanism that explains why some people experience irritable bowel syndrome (IBS) and other food intolerances when they eat certain foods.
IBS is a common problem thought to be experienced by up to 20% of the world’s population. It is currently viewed as a highly complex problem both in diagnosis and treatment. Some protocols that have proved effective in certain cases are gluten-free and other dietary recommendations. However, the mechanisms behind the successes have been a mystery, since the patients were not allergic to the foods in question, nor did they have known conditions such as celiac disease.
This new research revealed a mechanism that connects certain foods with activation of the mast cells that release histamine, and subsequent pain and discomfort.
Since people with IBS often report that their symptoms began after a gastrointestinal infection, such as food poisoning, scientists believe that certain foods might sensitize the immune system to that food. In this study, they tested this hypothesis by infecting mice with a stomach bug, and at the same time fed them ovalbumin, a protein found in egg white that is commonly used in experiments as a model food antigen. Once the infection cleared, the mice were given ovalbumin again, to see if their immune systems had become sensitized to it. The results were affirmative.
It was ascertained that the ovalbumin on its own provoked mast cell activation, histamine release, and consequent digestive intolerance with increased abdominal pain. This was not the case in mice that had not been infected with the bug and received ovalbumin.
The study then went on to see if people with IBS reacted in the same way. When food antigens associated with IBS (gluten, wheat, soy and cow milk) were injected into the intestine wall of 12 IBS patients, they produced localized immune reactions similar to that seen in the mice. No reaction was seen in healthy volunteers.
Due to the small number involved in the human trials, confirmation of these findings is required and indeed further clinical trials are already underway but knowing the mechanism that leads to mast cell activation is crucial and will lead to novel therapies for these patients, including the possibility of antihistamines.
Related Biotics Research Products:
Submit this form and you'll receive our latest news and updates.
The effect of a Mediterranean diet on both gastrointestinal (GI) and psychological symptoms among people with irritable ...
Learn moreResults of a double-blind randomized controlled trial were recently published in the Journal of Pediatric Gastroenterolo...
Learn moreA case series of 10 patients with long-standing, symptomatic, intractable drug-refractory irritable bowel syndrome (IBS)...
Learn more
*These statements have not been evaluated by the Food and Drug Administration. This product has not intended to diagnose, treat, cure, or prevent any disease.
© 2023 Biotics Research Corporation - All Rights Reserved
Submit your comment