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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
December 20 2024
The British Journal of Sports Medicine recently published a systematic review that analyzed the effects of postpartum exercise on maternal postpartum ...
The protective association between dietary flavonoid intake and the risk of dementia has been the focus of yet another study; this one being published recently in JAMA Network Open. Data from the UK Biobank, a prospective population-based cohort study, was analyzed not only to examine the relationship between flavonoids and all-cause dementia, but also to assess for any potential interactions with genetic risk of dementia, hypertension, and depressive symptoms.
Nearly 122,000 participants were included in the analysis, with a median follow-up of 9.4 years. At least two (and as many as 5) 24-hour validated food frequency questionnaires were used to assess dietary intake, and to calculate a “flavodiet score,” a composite total of the top food contributors to each flavonoid subclass. Genetic risk for dementia was considered high based upon either the presence of an APOE ε4 allele or being in the highest quintile of risk, (based upon a polygenic risk score defined elsewhere).
The median intake of flavonoids was 4.3 servings per day, 2.7 of which were from tea. People with the highest flavodiet scores also tended to exercise more, have a lower BMI, and have less socioeconomic deprivation. After multivariate adjustment for these factors, those in the highest quintile of intake (7.3 servings) had a 28% lower risk for dementia than those in the lowest quintile (1.4 servings). Tea, red wine, and berries appeared to account for the majority of the association with the flavodiet score; when these foods were removed from the analysis, it was no longer significant. The dementia risk reduction was even greater in those at high genetic risk (43% lower with high flavonoid intake), with depressive symptoms (48% lower), or hypertension (30% lower). Indeed, in the absence of these factors, no protective effect was observed. The most protective subclasses of flavonoids included anthocyanins, flavan-3-ols, flavonols, and flavones.
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