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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
November 21 2024
The protective association between dietary flavonoid intake and the risk of dementia has been the focus of yet another study; this one being published...
Results from a prospective cohort study based in Chicago were recently published in Neurology, describing the associations between dietary flavonol intake and cognitive decline. Nearly 1,000 older adults (average age 81) without dementia were followed for approximately 7 years, as part of the Rush Memory and Aging Project. Using annual validated food frequency questionnaires (self-reported) and standardized assessments of cognitive performance, a greater intake of dietary flavonols was associated with a slower rate of global cognitive decline, including multiple aspects of cognitive function, i.e., episodic, semantic, and working memory, as well as perceptual speed. These associations persisted after multivariate adjustment for factors such as age, sex, education, APOE-ɛ4, late-life cognitive activity, physical activity, and smoking. An analysis of individual flavonols found both kaempferol and quercetin to be associated with slower global cognitive decline.
Although this analysis was not able to show causality or pinpoint the mechanisms of action, flavonols such as quercetin have previously demonstrated not only anti-inflammatory and antioxidant effects, but have been shown to promote autophagy, promote mitochondrial function, and to have antitau and anti-Aβ actions. It should be emphasized that a diet rich in multiple flavonols and other compounds is likely to have multiple targets, a distinct advantage to single drug/nutrient approaches given that cognitive decline and dementia are most certainly multifactorial.
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