Subscribe

Receive updates about our latest products in your inbox

Register For Our Next Webinar

Beyond the Buzzword: Practical Detoxification Strategies for Clinicians

About Us

For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional

Search the Blog

  • There are no suggestions because the search field is empty.

Nutrients Turned to Toxins in Chronic Kidney Disease

3D_rendering_bacteriaOur gut microbiota process food nutrients in such a way that can generate uremic toxins or precursors metabolized to toxins in patients with chronic kidney disease (CKD). Some key uremic toxins include Trimethylamine N-Oxide (TMAO), p-cresyl-sulfate (pCS), indoxyl-sulfate (IS) and indole-3 acetic acid (IAA), all of which are important in the homeostasis and disposal of oxalate. TMAO is an amine oxide derived from dietary seafood, and has been associated with an increased risk of cardiac disease. New research shows uremic toxins may also be generated from dietary choline and D,L-carnitine. For healthy people, TMAO is excreted by the kidneys, but in individuals with CKD, it can accumulate as uremic toxins.

The authors of this study suggest that physicians explore the dietary habits of their CKD patients, and monitor their supplementation accordingly, to ensure there is no additional production of uremic toxins by their gut microbes. They recommend a close evaluation in dietary habits, and, also, the use of prebiotics and/or probiotics. 

 

Related Biotics Research Products:  BioDoph-7 Plus, BioDophilus Caps

Submit your comment

Related Post

Micronutrient Cocktail & Liver Health

The journal Medicina recently reported the results of a double-blind and placebo-controlled pilot clinical trial evaluat...

Learn more

Celebrate with Nutrient-Rich Summer Foods

As we celebrate the 4th of July, it’s the perfect time to enjoy the bounty of nutritious summer foods. A plethora of res...

Learn more

Nutrient Support for PCOS

A systematic review and network analysis was recently published in PeerJ, evaluating the randomized clinical trials of v...

Learn more