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eStoreRx™
Online Supplement Dispensary
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
July 17 2025
After over a half century of public health advice warning against diets high in saturated fat, the finger is starting to point toward oils rich in pol...
An analysis recently published in Cardiovascular Diabetology used a cluster-based approach to quantify the risk for developing type 2 diabetes (T2D) among older adults (aged 61-82). Building on a previously published proof-of-concept study, 843 participants in the Kora F4 study were assigned to one of six predefined phenotype clusters, with clusters determined by a number of metabolic and clinical characteristics shown to be predictive of diabetes incidence, mortality, and prediabetes complications in a middle-aged population.
Age, BMI, waist and hip circumference, fasting and 2-hour glucose and insulin were among the variables, with the 6 clusters roughly defined as follows (in order from 1 to 6): low risk, very low risk, beta-cell failure, low risk obese, high risk insulin-resistant fatty liver, and cluster 6, high risk visceral fat nephropathy. Additionally, a 73-analyte proteomics panel that included pro- and anti-inflammatory cytokines, chemokines, and other biomarkers of inflammation was included for each participant.
Clustering was associated with differences in T2D incidence as well as cardiometabolic risk, the incidence and prevalence of kidney disease and distal sensorimotor polyneuropathy, inflammatory load, and the prevalence of cardiovascular disease. For example, an odds ratio of at least 32 for T2D was found when comparing cluster 5, which had the highest incidence (53%), to cluster 2 with the lowest incidence (3.2%). The difference in inflammatory load was also the greatest between these two clusters. Notably, clusters 3 and 6 had an increase in the incidence of T2D, but did not have an elevation in inflammatory markers, pointing to potentially different pathways driving the diabetic process in different people, i.e., subtypes of diabetes. Lastly, it’s worth noting that although C-reactive protein was highest in cluster 5, it had only a small role in predicting inflammatory load. Given the heterogeneity among people with diabetes, understanding the factors underlying its development and risk is welcome.
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BMC Medicine recently published a post hoc analysis of the ADVANCE trial, describing the relationship between healthy li...
Learn moreThe Society of Metabolic Health Practitioners recently published a position statement on therapeutic carbohydrate reduct...
Learn moreJAMA Network Open recently published an analysis of several large cohorts of men and women, indicating a lower risk for ...
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