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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
December 04 2024
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A team of scientists has uncovered new information about the inflammatory effects of airborne particles from diesel fumes that can worsen asthma symptoms.
In recent years, it was shown in a large-scale study that a mutation in the chemical messengers that promote inflammation may be related to asthma. We have also discovered that higher levels of those chemical messengers, interleukin-33, may directly contribute to asthma severity.
However, a research team that has been looking at the mechanisms behind how asthma gets triggered has made an important discovery. They have revealed that a cell receptor called AhR is activated by diesel particles. The receptor promotes the production of inflammatory molecules that help rid the body of toxins in the body, yet overactivation of this receptor can cause health issues. It is found on cells in organs that are in contact with the air, including the skin, the gut, and the lungs.
In the collaborative study, the group stimulated human and mice immune cells with diesel particles that activated AhR. When stimulated, the cells produced IL-33, a specific chemical messenger that promotes inflammation. Yet when they were blocked, no IL-33 was generated by the cells. This suggests that diesel fumes aggravate immune cells to release chemicals that promote inflammation. This promising finding may help us understand the mechanisms behind many other chronic diseases of the skin, gut, and lungs.
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