Receive updates about our latest products in your inbox

Register For Our Next Webinar

Implementing the WholeLifeRx Program for Optimal Patient and Practice Outcomes

About Us

For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional

Search the Blog

    AMPK and Metabolic Health

    iStock-1160789077An apple a day keeps the doctor away, at least according to a new study  that shows apple polyphenols increase the activity of 5’ adenosine monophosphate-activated protein kinase (AMPK). Activation of AMPK may be a good way to lose weight, balance lipoproteins, and support healthy blood sugar.

    AMPK is a highly conserved sensor of adenosine nucleotide levels. Basically, it monitors energy, and is activated when ATP production decreases. Because AMPK inhibits fatty acid synthesis and increases fatty acid catabolism, researchers are investigating it as a possible pathway for weight loss. AMPK also inhibits HMG Co-A reductase, which influences cholesterol synthesis. 

    Exercise, of course, is one sure way to increase AMPK, according to studies. There are also phytochemicals that can increase AMPK, such as the polyphenol, berberine. Studies have shown that berberine has been reported to support healthy glucose and lipid levels. Berberine also promotes glucose consumption independent of AMPK activation, according to studies

    Green tea polyphenols can also increase phosphorylation of AMPK. One study suggests  the activation of AMPK as a potential mechanism by which green tea polyphenols regulate hepatic lipid metabolism in such a way that lipid synthesis is reduced and fat oxidation is stimulated.


    Related Biotics Research Product:



    Submit your comment

    Related Post

    Study Connects Biological Clock to Overeating and Obesity

    In a study published in the journal Current Biology, Güler and his team explored the connection between the pleasure cen...

    Learn more

    High Dietary Fiber Intake Improves Overall Health

    A review of studies and trials conducted over the last 40 years has shown that there is a link between eating more dieta...

    Learn more

    Why We Can't Stop Putting Our Hand in the Candy Dish

    A national team of researchers has identified a circuit in the brain that appears to regulate impulse control and be ass...

    Learn more