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For over 40 years, Biotics Research Corporation has revolutionized the nutritional supplement industry by utilizing “The Best of Science and Nature”. Combining nature’s principles with scientific ingenuity, our products magnify the nutritional
eStoreRx™ is an easy direct-to-patient ordering & fulfilment program for lifelong wellness.
Biotics Research is proud to expand our commitment to education with the Wellness Unfiltered Pro Podcast. Each episode delves into key health topics and the clinical applications of our premier products. Through candid, insightful conversations, our team offers practical guidance to keep you informed and empowered as a healthcare professional.
December 04 2024
People commonly adopt ketogenic diets with the goal of losing weight, but what about the other side of this: can keto help people – particularly those...
In an 1817 study on Parkinson’s disease (PD), James Parkinson noted that many of the patients with PD had gastrointestinal issues, and that up to 80% of these patients suffered from constipation. Even 200 years ago, we knew about the gut-brain connection. Currently, the literature demonstrates that the microbiome does, in fact, affect the function of the brain; the development of the brain, the activity of circuits in the brain, and certain behaviors. The research has mainly focused on identifying specific molecules made by gut bacteria, and how they mediate the gut-brain connection.
In a recent study, the question was posed, “Why do people with neurological conditions have GI issues?” Because the microbiomes are different between a PD patient and a healthy patient, they transplanted the microbiota from the human PD patients into germ-free mice. The mice, as you might expect, developed severe PD symptoms, confirming their theory that the microbiome was contributing to the symptoms.
In addition, the researchers identified the genes that are responsible for inducing PD symptoms, and recognized that these genes dictate microbial pathways. Their first clinical trial will begin at the end of the year, employing “a gut selective molecule that targets a microbial pathway, which is completely inert to the mammalian system, in about 100 PD patients.”
Whether or not the microbiome is responsible for inducing PD is “complete speculation,” as stated by the author of the study. However, they think that it is certainly possible. He also noted that decoding the microbiome will be a “blueprint that will uncover the microbiome as an avenue to understand health and disease and leverage it to people.”
In other words, the microbiome will continually be assessed to help demystify its influence on neurological diseases such as PD.
Ref.: Mazmanian S. Interview. Clinical OMICs November/December 2018 5(6):12-15.
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